A new medicine has been introduced to treat Keratinisation, an acute skin disorder and is an organic process by which keratin is deposited in cells and the cells become horny (as in nails and hair). In this process, the cytolplasm of the epidermis is replaced by Keratin. This can continue to grow and results in solid structures.

To treat this disease, rare medical combinations have been introduced. This is a very important medicine needed to treat acute as well as chronic skin disorders like keratinisation, ichthyosis, palmoplantar keratoderma, psoriasis, morphea, vitiligo, acanthosis nig-Ricans, Grovers disease and lichen sclerosus atropicus. The medicine is a com­bi­na­tion of cal­cipotriol+be­tametha­sone. Cal­cipotriol is a Vi­ta­min D3 de­riv­a­tive act­ing through Vi­ta­min D re­cep­tors to reg­u­late cell growth, dif­fer­en­ti­a­tion and im­mune functions.